Tacrolimus hemolysis

Transplant-associated thrombotic microangiopathy (TA-TMA) is an increasingly recognized complication of hematopoietic stem cell transplant (HSCT) with high morbidity and mortality. 1 Many patients with TMA have been reported to have a drug-induced etiology and many different drugs and other substances, including v Microangiopathic hemolytic anemia (MAHA) — MAHA is a descriptive term for non-immune hemolysis (ie, Coombs-negative hemolysis) resulting from intravascular red blood cell fragmentation that produces schistocytes on the peripheral blood smear ( picture 1) [ 1 ]

2024-03-29
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  1. , 1999; Astellas Pharma US, 2012 )
  2. 0-15
  3. 2017
  4. D
  5. Both the hemolysis and kidney injury resolve gradually
  6. ulcers or white spots in the mouth or on the lips
  7. 5 to 3
  8. Plasmapheresis x 15